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SAFC Pharma expands API manufacturing facility in Ireland

SAFC Pharma, a focus area within SAFC, a member of the Sigma-Aldrich Group, has announced that a new reactor at its Arklow, Ireland manufacturing site has begun operation, expanding the facility's capacity for large-scale active pharmaceutical ingredient manufacturing by approximately 15%.

The new reactor is the latest in a series of investments designed to enhance production capacity and expand capabilities at the Arklow site, which is the company’s global center for the production of commercial and late-stage active pharmaceutical ingredients (APIs) and advanced intermediates, the company said.

The $4-million project involved the installation and start-up of a 6,000 liter Hastalloy reactor for large-scale API manufacturing, increasing the total capacity at the site to 96,000 liters, with a reactor range from 250 to 8,000 liters. The company said that this latest investment adds capacity for both large- and small-scale manufacturing and improves upon the site’s award-winning environmental performance.

This latest investment complements two additional expansion projects at the Arklow site – the building of a $2.25-million, 15kg capacity pilot-scale filter dryer designed to double the facility’s current capacity for small-scale (10kg-150kg) manufacturing of APIs, due for commission in the third quarter of 2009, and a $1.8-million expansion of the site’s cGMP warehouse capacity, also scheduled for completion in 2009.

Michael Harris, SAFC Pharma Europe’s vice president, said: “Our continued investment in capabilities and capacity is a direct reflection of SAFC’s long-term commitment to meeting customer requirements for API manufacturing. Our continuing investments in facilities and personnel support the growth of SAFC Pharma and underline our position as an industry leader whose focus includes the responsibility to reduce our environmental footprint.”