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Positive mid-stage trial for Cerexa antibiotic

Cerexa has revealed positive top-line results for the phase II clinical trial of Ceftaroline for the treatment of complicated skin and skin structure infections.

In the trial, Ceftaroline was compared with the current standard therapy in 100 patients at 24 study sites worldwide. The clinical cure rate was 96.8% for subjects treated with Ceftaroline and 88.9% for those treated with the standard therapy of vancomycin, with or without adjunctive aztreonam.

According to the company, Ceftaroline also demonstrated excellent activity against gram-positive and gram-negative organisms isolated from patients in the study, including 100% of MRSA isolates inhibited at 0.5 mg/L or less.

“We’re very pleased with these results,” said Dennis Podlesak, CEO of Cerexa. “Ceftaroline’s high cure rates and broad spectrum of coverage clearly validate its potential as a potent first-line therapy with the significant added benefit of minimizing the need for combination therapy.”