Drug Discovery - Pre-clinical Studies

Existing drug offers targeted treatment for aggressive breast cancer

A new study claims palbociclib, an approved breast cancer drug, can treat an aggressive form of the cancer, bringing hope to thousands of afflicted women in the UK.

Eureka Therapeutics announces preclinical results of InvisiMask human antibody nasal spray against SARS-CoV-2 infection

Eureka Therapeutics announced successful preclinical results from its InvisiMask Human Antibody Nasal Spray in mice, which offers protection against SARS-CoV-2 S pseudotyped virus infection for up to 10 hours.

Sanofi, Translate Bio mRNA Covid-19 vaccine candidate induced high antibody levels in preclinical studies

Sanofi Pasteur, the vaccines global business unit of Sanofi, and Translate Bio (NASDAQ: TBIO), a clinical-stage messenger RNA (mRNA) therapeutics company, today announced the preclinical results for MRT5500, a mRNA-based vaccine candidate against SARS-CoV-2, the virus that causes COVID-19 disease.

BOLD-100 significantly outperforms remdesivir head-to-head in SARS-CoV-2 model

Bold Therapeutics, a clinical-stage biopharmaceutical company, recently generated additional data supporting rapid clinical development of BOLD-100 as a novel antiviral.

ImmunityBio’s hAd5 vaccine candidate for Covid-19 succeeds in preclinical study

ImmunityBio said that its human Ad5 vaccine candidate (hAd5 vaccine candidate), which is being developed for the prevention of Covid-19, has yielded positive preclinical results.

Catalent, Ennaid Therapeutics collaborate to develop antiviral treatment for Covid-19 disease

Catalent has collaborated with speciality pharmaceutical company Ennaid Therapeutics for the development of an oral and antiviral treatment for Covid-19 disease.

Vir, Alnylam to develop VIR-2703 RNAi therapeutic candidate for Covid-19 treatment

Vir Biotechnology and Alnylam Pharmaceuticals said that they have selected an investigational RNAi therapeutic called VIR-2703 which will be developed for targeting the SARS-CoV-2 genome for the treatment of Covid-19 (novel coronavirus).

Hoth Therapeutics announces agreement to joint development for a self-assembling vaccine (SAV) for the potential prevention of coronavirus

Hoth Therapeutics has reached an agreement with Voltron Therapeutics to form a joint venture entity, to be named HaloVax, to commence preclinical studies for the development of vaccine prospects to prevent the Coronavirus (COVID-19) based upon VaxCelerate.

RedHill Biopharma secures FDA approval for Talicia to treat H pylori infection in adults

Israeli biopharmaceutical firm RedHill Biopharma has secured the US Food and Drug Administration (FDA) approval for Talicia (omeprazole magnesium, amoxicillin and rifabutin) for the treatment of Helicobacter pylori (H. pylori) infection in adults.