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July 3, 2026

European Commission approves Novartis’ Itvisma to treat SMA

The European Commission has granted approval for Novartis’ Itvisma (onasemnogene abeparvovec) as a treatment for children two years and older, teenagers and adults who have 5q spinal muscular atrophy (SMA) with a bi-allelic mutation in the survival motor neuron 1 (SMN1) gene.

Itvisma works by providing a functional copy of the SMN1 gene, which is deficient in people with SMA. Credit: Andrzej Rostek/Shutterstock.com.