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April 16, 2026

Boehringer Ingelheim and Zai Lab team up for dual DLL3 therapy study

Boehringer Ingelheim and Zai Lab have entered a clinical collaboration to investigate a dual delta-like ligand 3 (DLL3)-targeting approach for patients with extensive-stage small cell lung cancer (ES-SCLC) and other neuroendocrine carcinomas (NECs).

Obrixtamig is an investigational bispecific DLL3 engager that targets DLL3-expressing cancer cells in SCLC and NECs. Credit: CI Photos / Shutterstock.com.