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CTL Laboratories


CTL Laboratories

Cellular Technology Limited (CTL) is a privately held biotechnology company that built its reputation as a global leader in the enzyme-linked immunospot (ELISPOT) field over the past two decades by establishing the ELISPOT instrumentation and scientific principles that have helped to define the parameters of ELISPOT research for monitoring of cell-mediated immunity.

Headquartered in Shaker Heights, OH, the company focuses on high-throughput ELISPOT assays, multiplex cytokine bead arrays (CBA), flow cytometry (such as phenotyping and multimer readouts), and BrdU proliferation assays.

CTL is uniquely capable of developing, qualifying and validating assays tailored to its clients’ specific needs in its good laboratory practice (GLP) compliant and Clinical Laboratory Improvement Amendments (CLIA) certified laboratory.


Cellular Technology Limited
20521 Chagrin Boulevard
Shaker Heights
OH 44122-5350

Phone: +1 216 791 5084
Fax: +1 216 791 8814

Analysis of Morphometric Bioassays with CTL’s BioSpot® Image Analysis Platform

Objective, scientifically validated counting algorithms ensure accurate results for yeast viability analysis, natural killer (NK) assays, viral plaque assays, clonogenic and genotoxicity assays, and bacterial colony counting. In recent years, Cellular Technology Limited (CTL) has further customised and optimised its instruments, introducing the BioSpot® Analysis Platform for various applications in the biotechnology and pharmaceutical industries…

Assay Standardisation for Monitoring of Cell Mediated Immunity

Access up to 2,000 vials of cryopreserved peripheral blood mononuclear cells (PBMC) from a single donor from CTL's extensive library of established antigen reactivity and high-resolution (HR) Human leukocyte antigen (HLA) typed healthy donors (more than 100) to enable standardisation of your cell-based assays. Supporting cell-based assay standardisation CTL provides comprehensive standardisation packages for cellular assays,…

ELISA, Multiplex, and Flow Cytometry Testing

CTL’s enzyme-linked immunospot (ELISPOT) assay expertise is complemented by its ELISA testing, multiplex cytometric bead array (CBA) and fluorescence-activated cell sorting (FACS) services. ELISA testing can be used to extract additional information on the production of antibodies or other cytokines from the same sample without requiring the use of additional blood draws. Similarly, flow cytometry can…

ELISPOT ImmunoSpot® Analysers

CTL's enzyme-linked immunospot (ELISPOT) assays are an effective readout system for cytokine-based immune monitoring and standardsation strategies. In addition to its Clinical Laboratory Improvement Amendments (CLIA) certified, good laboratory practice (GLP) compliant laboratory operations in which the company performs ELISPOT assays for its clients, CTL specialises in developing and manufacturing image-based analysis, high-throughput 21 CFR Part 11…

High-Throughput Immune Contract Laboratory Services

A four to five-week turnaround time for up to 1,000 subjects assayed for antigen-specific cytokine responses allows you to significantly accelerate immune monitoring of patient samples. CTL has many years of experience in performing contracted laboratory services. Its laboratory complies with Clinical Laboratory Improvement Amendments (CLIA) and US Food and Drug Administration (FDA) regulations, including…

Monitoring of Cell Mediated Immunity Focusing on T and B-Cells

CTL's enzyme-linked immunospot (ELISPOT) assays are effective readout systems for cytokine-based immune monitoring and standardisation strategies. ELISPOT assays and the related multiplex FluoroSpot technology are ideal for measurement of per-cell antigen-specific cytokine production and direct ex-vivo cytotoxicity assays. T-cell functional avidity studies and epitope mapping, and B-cell ELISPOT assays for determining the class or subclass of…

Specimen Management

CTL’s specimen management department is solely dedicated to monitoring pre-clinical and clinical samples from receipt to disposition. The company's thorough quality control measures ensure proper specimen handling and accurate data management. The movement of every specimen is tracked meticulously until CTL receives disposition instructions from the sponsor/client. CTL is a member of the International Society…

Specimen Processing

CTL provides laboratory services for processing and cryopreserving both pre-clinical and clinical specimens. Its scientific team has a wealth of experience in processing whole blood to obtain peripheral blood mononuclear cells (PBMC) or separate cell populations such as CD4, CD8, natural killer (NK) cells and monocytes. CTL also has experience in the processing of solid…

Contracted ELISPOT Testing for Immune Monitoring

CTL has years of experience in contracted research. Many pharmaceutical and biotechnology companies have entrusted CTL with evaluating cell-mediated immunity (CMI) to their vaccines, drugs, and biologic products using the enzyme-linked immunospot (ELISPOT) technique. Are you using the appropriate readout system for evaluating your test subject response? CTL's greatest strength lies in its high-throughput T-cell monitoring…
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Quick Contact CTL Laboratories

 Alliance Selects SCM for Sterile Product Supply

SPECIALITY pharmaceutical company Alliance Pharma has awarded a commercial supply contract for three of its products to sterile manufacturing expert...
26th August 2011
Quick Contact CTL Laboratories

Quick Contact CTL Laboratories

TVA™ – Non-Radioactive NK/ADCC Assessment

Traditionally, natural killer (NK) cell-mediated lysis of K562 tumour cells required laborious, time-consuming, radioactive chromium release assays (CRA). But no...
9th February 2016
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Quick Contact CTL Laboratories

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